Urinary Tract Infection (UTI)
Microbial Control

Scienetix Urinary Tract Infection (UTI) Microbial Control (UTI-MC) is a mixture of 6 heat-inactivated organisms (two gram-positive bacteria, two gram-negative bacteria, and two fungi) known to cause UTI. UTI-MC was prepared with organisms isolated from human urine and contains intact organisms that should be processed the same as human urine specimens. UTI-MC is suitable for evaluating DNA extraction methods and molecular diagnostic assays. The extraction control pool contains the easy-to-lyse gram-negative bacteria and fungi with rigid cell walls. Therefore, UTI-MC is suitable for investigating and eliminating nucleic acid extraction bias influencing diagnostic outcomes. Additionally, UTI-MC is ideal for developing and validating molecular diagnostics tools for UTIs.

  • Inactivated (heat-killed) whole organism pool.
  • Microbiologically characterized organisms.
  • Identity is confirmed by 16S/18S sequencing.
  • NGS verified composition.
  • qPCR and NGS validated Microbial composition.
  • Normalized (105 genomic copies/ML) composition.
  • Scienetix UTI-MC is suitable for evaluating qPCR and NGS assay performance for uropathogenic detection.
  • Validation of clinical UTI assays and training laboratory personnel.
  • Routine process control for NGS or qPCR based UTI testing

Instruction for Use

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  • Organisms were heat-killed to inactivate them before pooling. The inactivation was confirmed in a standard microbiological growth protocol.
  • UTI-MC contains inactivated microorganisms and is not biohazardous. However, standard precautions should be followed when handling UTI-MC to prevent cross-contamination.
  • For handling and disposal, consult the CDC recommendations and local regulations.
  • The matrix used in this product was manufactured from artificial urine tested by qPCR and NGS and found to contain no microorganisms
  • Do not use past labeled expiration date.
  • To avoid cross-contamination, use sterile tips.
Storage Conditions: -20°C or below
Species Class Source Genomic Copies/mL PCR (Ct of 1:10)
Enterococcus faecalis Gram Positive Lab-isolate 1.00E+05 27.57
Enterococcus faecium Gram Positive Lab-isolate 1.00E+05 27.81
Klebsiella pneumoniae Gram Negative Lab-isolate 1.00E+05 27.44
Escherichia coli Gram Negative Lab-isolate 1.00E+05 27.21
Candida albicans Fungi Lab-isolate 1.00E+05 26.39
Candida glabrata Fungi Lab-isolate 1.00E+05 26.08

For Research Use Only

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